The European Commission published its first list of critical medicines, as part of a wider overhaul of laws governing the 136 billion euro ($148 billion) pharmaceuticals industry aimed at avoiding shortages of drugs. It is the biggest change to existing medical laws in two decades. The list, published by the European Medicines Agency, includes a wide range of essential, generic medicines from basic antibiotics such as amoxicillin, painkillers like paracetamol and morphine, and insulin used to treat diabetes. It includes some vaccines for measles, hepatitis B and tetanus, among others.